EMD-47429

Single-particle
3.3 Å
EMD-47429
3D View Gallery
Deposition: 21/10/2024
Map released: 09/07/2025
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47429
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9e22 summary report (pdf.gz) Map and 9e22 FULL report (pdf.gz)
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Cryo-EM structure of human cytoplasmic dynein-1 bound to LIS1 in the presence of ATP

EMD-47429

Single-particle
3.3 Å
EMD-47429
3D View Gallery
Deposition: 21/10/2024
Map released: 09/07/2025
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human Cytoplasmic dynein-1 bound to LIS1
Fitted models: 9e22

Deposition Authors: Nguyen KHV, Kendrick AA, Leschziner AE
Cryo-EM captures early intermediate steps in dynein activation by LIS1.
Nguyen KHV, Karasmanis EP, Kendrick AA, Reck-Peterson SL, Leschziner AE
(2025) Nat Commun , 16 , 7054 - 7054
PUBMED: 40750582
DOI: doi:10.1038/s41467-025-62185-z
ISSN: 2041-1723