EMD-47002

Helical reconstruction
3.2 Å
EMD-47002 Deposition: 13/09/2024
Map released: 23/04/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47002

Type 3 KD-mxyl filament of miniature tau macrocycle derived from 4R tauopathic fold

EMD-47002

Helical reconstruction
3.2 Å
EMD-47002 Deposition: 13/09/2024
Map released: 23/04/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Type 3 KD-mxyl filament of miniature tau macrocycle derived from 4R tauopathic fold
Fitted models: 9dme

Deposition Authors: Xu X , Angera JI , Rajewski HB , Jiang W , Del Valle RJ
Macrocyclic beta-arch peptides that mimic the structure and function of disease-associated tau folds.
Angera IJ, Xu X , Rajewski BH, Hallinan GI, Zhang X, Ghetti B, Vidal R, Jiang W , Del Valle JR
(2025) Nat Chem , 17 , 865 - 874
PUBMED: 40307419
DOI: doi:10.1038/s41557-025-01805-z
ISSN: 1755-4349