EMD-46977

Helical reconstruction
5.6 Å
EMD-46977
3D View Gallery
Deposition: 11/09/2024
Map released: 22/01/2025
Last modified: 29/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46977
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9dlg summary report (pdf.gz) Map and 9dlg FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of the TIR domain from human TRAM

EMD-46977

Helical reconstruction
5.6 Å
EMD-46977
3D View Gallery
Deposition: 11/09/2024
Map released: 22/01/2025
Last modified: 29/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Self-assembly of TIR domain of TRIF-related adaptor protein (TRAM)
Fitted models: 9dlg

Deposition Authors: Hedger A, Pospich S , Pan M , Gu W, Ve T, Raunser S , Landsberg M, Nanson JD , Kobe B
Structural basis for TIR domain-mediated innate immune signaling by Toll-like receptor adaptors TRIF and TRAM.
Manik MK , Pan M , Xiao L, Gu W, Kim H, Pospich S , Hedger A, Vajjhala PR, Lee MYL, Qian X, Landsberg MJ, Ve T, Nanson JD , Raunser S , Stacey KJ, Wu H , Kobe B
(2025) PNAS , 122 , e2418988122 - e2418988122
PUBMED: 39786929
DOI: doi:10.1073/pnas.2418988122
ISSN: 1091-6490
ASTM: PNASA6