EMD-46915

Helical reconstruction
3.32 Å
EMD-46915
3D View Gallery
Deposition: 05/09/2024
Map released: 12/03/2025
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46915
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

Recombinant AD-fold Quadruple Helical Filament Polymorph

EMD-46915

Helical reconstruction
3.32 Å
EMD-46915
3D View Gallery
Deposition: 05/09/2024
Map released: 12/03/2025
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Truncated tau 287-391

Deposition Authors: Vaquer-Alicea J , Diamond MI , Kunach P
Functional classification of tauopathy strains reveals the role of protofilament core residues.
Vaquer-Alicea J , Manon VA, Bommareddy V , Kunach P , Gupta A , Monistrol J , Perez VA , Tran HT, Saez-Calveras N , Du S , Batra S , Stoddard D , White 3rd CL , Joachimiak LA , Shahmoradian SH , Diamond MI
(2025) Sci Adv , 11 , eadp5978 - eadp5978
PUBMED: 39841851
DOI: doi:10.1126/sciadv.adp5978
ISSN: 2375-2548