EMD-46788
VFLIP Spike Trimer with 4C12-B12
EMD-46788
Single-particle3.18 Å
Deposition: 28/08/2024Map released: 15/01/2025
Last modified: 22/01/2025
Sample Organism:
Homo sapiens
Sample: VFLIP Spike trimer with 4C12-B12 FAB
Deposition Authors: Sobti M
,
Stewart AG
Sample: VFLIP Spike trimer with 4C12-B12 FAB
Deposition Authors: Sobti M
,
Stewart AG
Affinity maturation endows potent activity onto class 6 SARS-CoV-2 broadly neutralizing antibodies.
Mazigi O,
Langley DB ,
Henry JY,
Burnett DL,
Sobti M ,
Walker GJ ,
Rouet R,
Balachandran H,
Lenthall H,
Jackson J ,
Ubiparipovic S,
Schofield P,
Brown SHJ,
Schulz SR ,
Hoffmann M ,
Pohlmann S ,
Post J ,
Martinello M,
Ahlenstiel G ,
Kelleher A,
Rawlinson WD ,
Turville SG,
Bull RA ,
Stewart AG,
Jack HM ,
Goodnow CC ,
Christ D
(2025) PNAS , 122 , e2417544121 - e2417544121
,
Henry JY,
Burnett DL,
Sobti M ,
Walker GJ ,
Rouet R,
Balachandran H,
Lenthall H,
Jackson J ,
Ubiparipovic S,
Schofield P,
Brown SHJ,
Schulz SR ,
Hoffmann M ,
Pohlmann S ,
Post J ,
Martinello M,
Ahlenstiel G ,
Kelleher A,
Rawlinson WD ,
Turville SG,
Bull RA ,
Stewart AG,
Jack HM ,
Goodnow CC ,
Christ D
(2025) PNAS , 122 , e2417544121 - e2417544121
Grant Support:
- Australian Research Council (ARC): (Australia)