EMD-46759

Single-particle
4.1 Å
EMD-46759
3D View Gallery
Deposition: 27/08/2024
Map released: 10/09/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46759
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9dd7 summary report (pdf.gz) Map and 9dd7 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of neutralizing human antibody D48 in complex with HSV-1 glycoprotein B trimer gB-Ecto.516P.531E.DS

EMD-46759

Single-particle
4.1 Å
EMD-46759
3D View Gallery
Deposition: 27/08/2024
Map released: 10/09/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Human alphaherpesvirus 1
Sample: D48 Fab in complex with HSV-1 gB trimer
Fitted models: 9dd7

Deposition Authors: Roark RS, Shapiro L, Kwong PD
Prefusion structure, evasion and neutralization of HSV-1 glycoprotein B.
Roark RS, Schaub AJ, Shi W, Wang M, Bahna FA, Becker JE, Biju A, Chong S, Du H, Guo Y, Hong H, Katsamba PS, Mannepalli SM, Olia AS, Ou L, Rubin SK, Sabo Y, Suleiman M, Wells ML, Zhang B, Cheng C, Glasgow A, Ho DD, Huang Y, Pierson TC, Rawi R, Zhou T, Shapiro L, Kwong PD
(2025) Nat Microbiol , 10 , 2966 - 2980
PUBMED: 41174178
DOI: doi:10.1038/s41564-025-02153-x
ISSN: 2058-5276