EMD-46715

Single-particle
20.0 Å
EMD-46715
3D View Gallery
Deposition: 23/08/2024
Map released: 19/02/2025
Last modified: 19/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46715
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
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EMICSS annotations (xml)

MERS NTD-specific polyclonal antibodies

EMD-46715

Single-particle
20.0 Å
EMD-46715
3D View Gallery
Deposition: 23/08/2024
Map released: 19/02/2025
Last modified: 19/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Middle East respiratory syndrome-related coronavirus
Sample: MERS spike protein complexed with RBD-depleted polyclonal Fabs from MERS-vaccinated mice sera

Deposition Authors: Ward AB, Bangaru S
MERS-CoV spike vaccine-induced N-terminal domain-specific antibodies are more protective than receptor binding domain-specific antibodies.
Abiona OM, Wang N, Leist SR, Schafer A, Cockrell AS, Wang L, Bangaru S, Stevens L, Graham RL, Kocher JF, Tsybovsky Y, Kanekiyo M, Kumar A, Morabito KM, Rosen O, Shi W, Werner A, Zhang Y, Ziwawo C, Dzuvor CKO, Palandjian C, Eastman C, Matthews HR, Joseph J , Chappell JD, Kong WP, Mascola JR, Ward AB, Denison MR, Baric R, McLellan JS , Graham BS, Corbett-Helaire KS
(2025) iScience , 28 , 111632 - 111632
PUBMED: 39898019
DOI: doi:10.1016/j.isci.2024.111632
ISSN: 2589-0042