EMD-46715
MERS NTD-specific polyclonal antibodies
EMD-46715
Single-particle20.0 Å
Deposition: 23/08/2024Map released: 19/02/2025
Last modified: 19/02/2025
Sample Organism:
Middle East respiratory syndrome-related coronavirus
Sample: MERS spike protein complexed with RBD-depleted polyclonal Fabs from MERS-vaccinated mice sera
Deposition Authors: Ward AB, Bangaru S
Sample: MERS spike protein complexed with RBD-depleted polyclonal Fabs from MERS-vaccinated mice sera
Deposition Authors: Ward AB, Bangaru S
MERS-CoV spike vaccine-induced N-terminal domain-specific antibodies are more protective than receptor binding domain-specific antibodies.
Abiona OM,
Wang N,
Leist SR,
Schafer A,
Cockrell AS,
Wang L,
Bangaru S,
Stevens L,
Graham RL,
Kocher JF,
Tsybovsky Y,
Kanekiyo M 
,
Kumar A,
Morabito KM,
Rosen O,
Shi W,
Werner A,
Zhang Y,
Ziwawo C,
Dzuvor CKO,
Palandjian C,
Eastman C,
Matthews HR,
Joseph J ,
Chappell JD,
Kong WP,
Mascola JR,
Ward AB,
Denison MR,
Baric R,
McLellan JS ,
Graham BS,
Corbett-Helaire KS
(2025) iScience , 28 , 111632 - 111632
,
Kumar A,
Morabito KM,
Rosen O,
Shi W,
Werner A,
Zhang Y,
Ziwawo C,
Dzuvor CKO,
Palandjian C,
Eastman C,
Matthews HR,
Joseph J ,
Chappell JD,
Kong WP,
Mascola JR,
Ward AB,
Denison MR,
Baric R,
McLellan JS ,
Graham BS,
Corbett-Helaire KS
(2025) iScience , 28 , 111632 - 111632
Grant Support:
- Bill & Melinda Gates Foundation: OPP1170236 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): P01 AI110657 (United States)