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EMD-46699

Single-particle
2.8 Å
EMD-46699
3D View Gallery
Deposition: 22/08/2024
Map released: 17/12/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46699
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9dav summary report (pdf.gz) Map and 9dav FULL report (pdf.gz)
EMICSS annotations (xml)

STING oligomer bound to cGAMP and STG2 in the presence of PI4P

EMD-46699

Single-particle
2.8 Å
EMD-46699
3D View Gallery
Deposition: 22/08/2024
Map released: 17/12/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: STING oligomer bound to its ligand cGAMP, a synthetic activator named STG2, in the presence of Cholesteryl hemisuccinate and PI4P
Fitted models: 9dav

Deposition Authors: Li J , Zhang X , Bai X

Structural basis for the roles of phosphoinositide phosphates and cholesterol in STING activation
Jie L, Zhang X , Bai X
To Be Published