Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-46692

Single-particle
3.7 Å
EMD-46692 Deposition: 22/08/2024
Map released: 17/12/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46692

S. thermophilus class III ribonucleotide reductase signal subtracted cone domains and core

EMD-46692

Single-particle
3.7 Å
EMD-46692 Deposition: 22/08/2024
Map released: 17/12/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Streptococcus thermophilus
Sample: S. thermophilus class III ribonucleotide reductase dimer with allosteric effectors dATP and TTP

Deposition Authors: Andree GA , Drennan CL
How ATP and dATP reposition class III ribonucleotide reductase cone domains to regulate enzyme activity.
Andree GA , Miller-Brown KR , Zhao Z , Smith AK , Dawson CD, Deredge DJ , Drennan CL
(2025) Sci Adv , 11 , eady9156 - eady9156
PUBMED: 41313771
DOI: doi:10.1126/sciadv.ady9156
ISSN: 2375-2548