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EMD-46646
HIV-1 BaL Env in complex with CD4 mimetic CJF-III-288 and 17b IgG
EMD-46646
Subtomogram averaging21.5 Å
Deposition: 20/08/2024Map released: 16/10/2024
Last modified: 16/10/2024
Sample Organism:
Human immunodeficiency virus 1
Sample: Human immunodeficiency virus 1
Deposition Authors: Grunst MW
Sample: Human immunodeficiency virus 1
Deposition Authors: Grunst MW
The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC.
Richard J,
Grunst MW ,
Niu L,
Diaz-Salinas MA,
Tolbert WD,
Marchitto L,
Zhou F,
Bourassa C,
Yang D,
Chiu TJ,
Chen HC,
Benlarbi M,
Gottumukkala S,
Li W,
Dionne K,
Belanger E,
Chatterjee D,
Medjahed H,
Hendrickson WA,
Sodroski J,
Lang ZC,
Morton AJ,
Huang RK,
Matthies D ,
Smith 3rd AB,
Mothes W,
Munro JB ,
Pazgier M,
Finzi A
(2024) bioRxiv
,
Niu L,
Diaz-Salinas MA,
Tolbert WD,
Marchitto L,
Zhou F,
Bourassa C,
Yang D,
Chiu TJ,
Chen HC,
Benlarbi M,
Gottumukkala S,
Li W,
Dionne K,
Belanger E,
Chatterjee D,
Medjahed H,
Hendrickson WA,
Sodroski J,
Lang ZC,
Morton AJ,
Huang RK,
Matthies D ,
Smith 3rd AB,
Mothes W,
Munro JB ,
Pazgier M,
Finzi A
(2024) bioRxiv
Grant Support:
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): R37AI150560 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): R01AI176904 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): P01AI150471 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): F31AI176650 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): T32 AI055403 (United States)