EMD-46602

Composite map
Single-particle
3.31 Å
EMD-46602
3D View Gallery
Deposition: 16/08/2024
Map released: 11/02/2026
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46602
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9d74 summary report (pdf.gz) Map and 9d74 FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of anti-MHC-I Fab B1.23.2 complex with HLA-B44:05

EMD-46602

Composite map
Single-particle
3.31 Å
EMD-46602
3D View Gallery
Deposition: 16/08/2024
Map released: 11/02/2026
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Complex of Anti-human-mAb B1.23.2 Fab and MHC-I HLA-B44:05
Fitted models: 9d74

Deposition Authors: Jiang J , Natarajan K , Margulies DH , Lei H , Huang R
Structural mechanism of anti-MHC-I antibody blocking of inhibitory NK cell receptors in tumor immunity.
Jiang J , Panda AK, Natarajan K , Lei H , Sharma S, Boyd LF, Towler RR , Chempati S, Ahmad J, Morton AJ, Lang ZC, Sun Y, Sgourakis N , Meier-Schellersheim M , Huang RK, Shevach EM , Margulies DH
(2026) Commun Biol
PUBMED: 41629525
DOI: doi:10.1038/s42003-026-09641-8
ISSN: 2399-3642