EMD-46600

Single-particle
2.67 Å
EMD-46600
3D View Gallery
Deposition: 16/08/2024
Map released: 04/02/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46600

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9d72 summary report (pdf.gz) Map-9d72 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of anti-MHC-I Fab M1/42 complex with H2-Dd

EMD-46600

Single-particle
2.67 Å
EMD-46600
3D View Gallery
Deposition: 16/08/2024
Map released: 04/02/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus, Mus musculus, synthetic construct
Sample: Complex of Anti mouse Fab M1/42 and MHC-I H2-Dd
Fitted models: 9d72

Deposition Authors: Jiang J , Natarajan K , Margulies DH , Lei H , Huang R
Structural mechanism of anti-MHC-I antibody blocking of inhibitory NK cell receptors in tumor immunity.
Jiang J , Panda AK, Natarajan K , Lei H , Sharma S, Boyd LF, Towler RR , Chempati S, Ahmad J, Morton AJ, Lang ZC, Sun Y, Sgourakis N , Meier-Schellersheim M , Huang RK, Shevach EM , Margulies DH
(2025) Res Sq
PUBMED: 41333432
DOI: doi:10.21203/rs.3.rs-7133881/v1
ISSN: 2693-5015