EMD-46596

Single-particle
4.24 Å
EMD-46596
3D View Gallery
Deposition: 15/08/2024
Map released: 05/02/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46596
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9d6f summary report (pdf.gz) Map and 9d6f FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of E. coli FimH lectin domain bound to Fabs 440-2 and 454-3

EMD-46596

Single-particle
4.24 Å
EMD-46596
3D View Gallery
Deposition: 15/08/2024
Map released: 05/02/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Escherichia coli
Sample: FimH-DSG TM in complex with Fabs 440-2 and 445-3
Fitted models: 9d6f

Deposition Authors: Lees JA , Han S
Structure-based design of an immunogenic, conformationally stabilized FimH antigen for a urinary tract infection vaccine.
Silmon de Monerri NC , Che Y, Lees JA , Jasti J, Wu H, Griffor MC, Kodali S, Hawkins JC, Lypowy J, Ponce C, Curley K, Esadze A, Carcamo J, McLellan T, Keeney D, Illenberger A, Matsuka YV, Shanker S, Chorro L, Gribenko AV, Han S, Anderson AS, Donald RGK
(2025) PLoS Pathog , 21 , e1012325 - e1012325
PUBMED: 39970181
DOI: doi:10.1371/journal.ppat.1012325
ISSN: 1553-7374
Grant Support: