EMD-46481

Helical reconstruction
3.18 Å
EMD-46481
3D View Gallery
Deposition: 08/08/2024
Map released: 13/08/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46481
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9d23 summary report (pdf.gz) Map and 9d23 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of amyloid fibril extracted from heart of a variant ATTR T60A amyloidosis patient 2

EMD-46481

Helical reconstruction
3.18 Å
EMD-46481
3D View Gallery
Deposition: 08/08/2024
Map released: 13/08/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cardiac amyloid fibril of a variant ATTR T60A amyloidosis patient
Fitted models: 9d23

Deposition Authors: Nguyen AB , Fernandez-Ramirez MC , Saelices L
Structural and molecular homogeneity of ATTRv-T60A amyloid fibrils across patients and organs.
Fernandez-Ramirez MDC, Nguyen BA , Afrin S, Singh V, Evers B, Shelton JM, Escobar CL, Bassett P, Wang L, Pekala M, Ahmed Y, Cabrera Hernandez LO, Pedretti R, Singh P, Canepa J, Wosztyl A, Li Y, Boyer DR, Cao Q, Saelices L
(2025) Structure , 33 , 2013 - 2019.e4
PUBMED: 41106377
DOI: doi:10.1016/j.str.2025.09.008
ISSN: 0969-2126
ASTM: STRUE6