EMDB < EMD-45873

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

EMD-45873

Single-particle
3.5 Å

EMD-45873

3D View Gallery

Deposition: 22/07/2024
Map released: 13/08/2025
Last modified: 13/08/2025

Overview 3D View Sample Experiment Validation Additional data Links

Overview 3D View Sample Experiment Validation Additional data Links

EMD-45873

Download

Post-targeting aCascade Type IA CRISPR-Cas Surveillance Complexes

EMD-45873

Single-particle
3.5 Å
EMD-45873

EMD-45873

3D View Gallery

Deposition: 22/07/2024
Map released: 13/08/2025
Last modified: 13/08/2025

Overview 3D View Sample Experiment Validation Additional data Links

Sample Organism: Saccharolobus solfataricus P2, Saccharolobus solfataricus
Sample: Type I-A CRISPR_Cas post-targeting surveillance subcomplex from Saccharolobus solfataricus
Fitted models: 9cro

Deposition Authors: Findlay JL , Gentry JK, Lawrence CM

Structures and Disassembly of Post-Targeting Type I-A CRISPR-Cas Surveillance Complexes

Findlay JL , Gentry JK, Lawrence CM
To Be Published

Grant Support:

National Science Foundation (NSF, United States): DBI-1828765 (United States)
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): P30GM140963 (United States)