EMD-45795

Single-particle
3.4 Å
EMD-45795
3D View Gallery
Deposition: 17/07/2024
Map released: 02/10/2024
Last modified: 02/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45795

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Focused refinement of the Heptahelical transmembrane (7TM) domain of the calcium-sensing receptor

EMD-45795

Single-particle
3.4 Å
EMD-45795
3D View Gallery
Deposition: 17/07/2024
Map released: 02/10/2024
Last modified: 02/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Calcium-sensing receptor bound to compound '6218

Deposition Authors: Wu C, Skiniotis G
Large library docking identifies positive allosteric modulators of the calcium-sensing receptor.
Liu F , Wu CG , Tu CL, Glenn I, Meyerowitz J, Kaplan AL , Lyu J , Cheng Z, Tarkhanova OO , Moroz YS , Irwin JJ , Chang W , Shoichet BK , Skiniotis G
(2024) Science , 385 , eado1868 - eado1868
PUBMED: 39298584
DOI: doi:10.1126/science.ado1868
ISSN: 1095-9203
ASTM: SCIEAS