EMD-45752

Single-particle
3.3 Å
EMD-45752
3D View Gallery
Deposition: 15/07/2024
Map released: 11/12/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45752

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9cmp summary report (pdf.gz) Map-9cmp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of human Argonaute2-guide-target complex in a fully paired, slicing-competent conformation

EMD-45752

Single-particle
3.3 Å
EMD-45752
3D View Gallery
Deposition: 15/07/2024
Map released: 11/12/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: miR7-HsAGO2 RISC
Fitted models: 9cmp

Deposition Authors: Mohamed AA, Wang PY , Bartel DP, Vos SM
The structural basis for RNA slicing by human Argonaute2.
Mohamed AA, Wang PY , Bartel DP, Vos SM
(2025) Cell Rep , 44 , 115166 - 115166
PUBMED: 39932188
DOI: doi:10.1016/j.celrep.2024.115166
ISSN: 2211-1247