EMD-45578

Single-particle
2.94 Å
EMD-45578
3D View Gallery
Deposition: 28/06/2024
Map released: 02/07/2025
Last modified: 14/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45578
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9cg9 summary report (pdf.gz) Map and 9cg9 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of an HMGB1 box bound to nucleosome at SHL-2

EMD-45578

Single-particle
2.94 Å
EMD-45578
3D View Gallery
Deposition: 28/06/2024
Map released: 02/07/2025
Last modified: 14/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Xenopus laevis, Homo sapiens, synthetic construct
Sample: Complex of nucleosome with HMGB1
Fitted models: 9cg9

Deposition Authors: Chio US , Saunders HS, Narlikar GJ , Cheng Y
HMGB1 deforms nucleosomal DNA to generate a dynamic chromatin environment counteracting the effects of linker histone.
Saunders HS, Chio US , Moore CM , Ramani V , Cheng Y , Narlikar GJ
(2025) Sci Adv , 11 , eads4473 - eads4473
PUBMED: 40815652
DOI: doi:10.1126/sciadv.ads4473
ISSN: 2375-2548