EMD-45577

Single-particle
3.5 Å
EMD-45577
3D View Gallery
Deposition: 28/06/2024
Map released: 22/01/2025
Last modified: 05/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45577

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM Structural Analysis of Human Integrin Heterodimer bound to DNA Aptamer

EMD-45577

Single-particle
3.5 Å
EMD-45577
3D View Gallery
Deposition: 28/06/2024
Map released: 22/01/2025
Last modified: 05/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: human integrin alpha4 beta1 heterodimer in complex with DNA aptamer

Deposition Authors: Wang T
DNA Aptamer-Polymer Conjugates for Selective Targeting of Integrin alpha 4 beta 1 + T-Lineage Cancers.
Cardle II, Raman J , Nguyen DC , Wang T , Wu AY , Sellers DL , Pichon TJ, Cheng EL, Kacherovsky N, Salipante SJ, Jensen MC, Pun SH
(2025) ACS Appl Mater Interfaces , 17 , 4543 - 4561
PUBMED: 39788927
DOI: doi:10.1021/acsami.4c17788
ISSN: 1944-8252
Grant Support: