EMDB EMD-4556

Single particle reconstruction
3.97Å resolution

Truncated human R2TP complex, structure 5 (ADP-filled)

Map released:
Overview of EMD-4556
Source organism: Homo sapiens [9606]
Primary publication:
Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM
Munoz-Hernandez H, Pal M, Rodriguez CF, Fernandez-Leiro R, Prodromou C, Pearl LH, Llorca O
Sci Adv - (2019)

Function and Biology Details

Sample name: RUVBL1-RUVBL2 in a closed conformation with ADP
Proteins: RUVBL1-RUVBL2 in a closed conformation with ADP, RuvB-like 1, RuvB-like 2, PIH1 domain-containing protein 1, RNA polymerase II-associated protein 3

Experimental Information Details

Resolution: 3.97Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)