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EMD-45530

Single-particle
3.5 Å
EMD-45530
3D View Gallery
Deposition: 27/06/2024
Map released: 19/11/2025
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45530
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9cf5 summary report (pdf.gz) Map and 9cf5 FULL report (pdf.gz)
EMICSS annotations (xml)

STRUCTURE OF CD4 MIMETIC CJF-III-288 IN COMPLEX WITH BG505 SOSIP.664 HIV-1ENV TRIMER AND 17B FAB

EMD-45530

Single-particle
3.5 Å
EMD-45530
3D View Gallery
Deposition: 27/06/2024
Map released: 19/11/2025
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Human immunodeficiency virus 1, Homo sapiens
Sample: Complex of BG505 SOSIP.664 Env trimer with CJF-III-288 and three bound 17b FABS.
Fitted models: 9cf5

Deposition Authors: Niu L, Tolbert WD, Pazgier M
The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC.
Richard J, Grunst MW, Niu L, Diaz-Salinas MA, Tolbert WD, Marchitto L, Zhou F, Bourassa C, Yang D, Chiu TJ, Chen HC, Benlarbi M, Gottumukkala S, Li W, Dionne K, Belanger E, Chatterjee D, Medjahed H, Hendrickson WA, Sodroski J, Lang ZC, Morton AJ, Huang RK, Matthies D , Smith 3rd AB, Mothes W, Munro JB , Pazgier M, Finzi A
(2024) bioRxiv
PUBMED: 39253431
DOI: doi:10.1101/2024.08.27.609961
ISSN: 2692-8205