EMDB EMD-4553

Single particle reconstruction
4.63Å resolution

Truncated human R2TP complex, structure 4 (ADP-empty)

Map released:
Overview of EMD-4553
Source organism: Homo sapiens [9606]
Fitted atomic model: 6qi9
Related EM entries by publication: EMD-4552, EMD-4554, EMD-4555, EMD-4556, EMD-4557
Primary publication:
Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM.
Munoz-Hernandez H, Pal M, Rodriguez CF, Fernandez-Leiro R, Prodromou C, Pearl LH, Llorca O
Sci Adv 5 eaaw1616-eaaw1616 (2019)
PMID: 31049401

Function and Biology Details

Sample name: RUVBL1-RUVBL2 in an open conformation (ADP-empty)
Ligand: ADENOSINE-5'-DIPHOSPHATE
Proteins: RUVBL1-RUVBL2 in an open conformation (ADP-empty), RuvB-like 1, RuvB-like 2

Experimental Information Details

Resolution: 4.63Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)