EMDB EMD-4552

Single particle reconstruction
3.75Å resolution

Truncated human R2TP complex, structure 3 (ADP-filled)

Map released:
Last modified:
Overview of EMD-4552
Source organism: Homo sapiens [9606]
Fitted atomic model: 6qi8
Primary publication:
Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM
Munoz-Hernandez H, Pal M, Rodriguez CF, Fernandez-Leiro R, Prodromou C, Pearl LH, Llorca O
Sci Adv - (2019)

Function and Biology Details

Sample name: RUVBL1-RUVBL2 in a closed conformation (ADP-filled)
Ligand: ADENOSINE-5'-DIPHOSPHATE
Proteins: RUVBL1-RUVBL2 in a closed conformation (ADP-filled), RuvB-like 1, RuvB-like 2

Experimental Information Details

Resolution: 3.75Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)