EMD-45412

Single-particle
4.24 Å
EMD-45412
3D View Gallery
Deposition: 18/06/2024
Map released: 28/05/2025
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45412

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9cb1 summary report (pdf.gz) Map-9cb1 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM Structure of the Human Neutralizing Antibody 5-1 in Complex with Prefusion Human Metapneumovirus F Glycoprotein

EMD-45412

Single-particle
4.24 Å
EMD-45412
3D View Gallery
Deposition: 18/06/2024
Map released: 28/05/2025
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, human metapneumovirus
Sample: The protein complex of hMPV F-DsCavEs2-IPDS and 5-1 Fab
Fitted models: 9cb1

Deposition Authors: Guo LQ, McLellan JS
A potently neutralizing and protective human antibody targeting antigenic site V on RSV and hMPV fusion glycoprotein.
Abu-Shmais AA, Guo L, Khalil AM, Leonard SE, Miller RJ, Janke AK, Vukovich MJ, Bass LE, Suresh YP, Rush SA, Wolters RM, Kose N, Carnahan RH, Crowe Jr JE, Bonami RH, Mousa JJ, McLellan JS, Georgiev IS
(2026) Cell Rep Med , 7 , 102564 - 102564
PUBMED: 41547352
DOI: doi:10.1016/j.xcrm.2025.102564
ISSN: 2666-3791
Grant Support: