EMD-45360

Single-particle
3.0 Å
EMD-45360
3D View Gallery
Deposition: 13/06/2024
Map released: 22/01/2025
Last modified: 29/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45360

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9c96 summary report (pdf.gz) Map-9c96 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of TAP binding protein related (TAPBPR) in complex with HLA-A*02:01 bound to a suboptimal peptide.

EMD-45360

Single-particle
3.0 Å
EMD-45360
3D View Gallery
Deposition: 13/06/2024
Map released: 22/01/2025
Last modified: 29/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of peptide loaded HLA-A*02:01/beta-2-microglobulin in complex with human TAPBPR.
Fitted models: 9c96

Deposition Authors: Pumroy RP, Mallik L, Sun Y, Moiseenkova-Bell YV, Sgourakis NG
CryoEM structure of an MHC-I/TAPBPR peptide-bound intermediate reveals the mechanism of antigen proofreading.
Sun Y, Pumroy RA , Mallik L, Chaudhuri A, Wang C, Hwang D , Danon JN , Dasteh Goli K, Moiseenkova-Bell VY , Sgourakis NG
(2025) PNAS , 122 , e2416992122 - e2416992122
PUBMED: 39786927
DOI: doi:10.1073/pnas.2416992122
ISSN: 1091-6490
ASTM: PNASA6