EMD-45296

Single-particle
3.24 Å
EMD-45296
3D View Gallery
Deposition: 11/06/2024
Map released: 08/01/2025
Last modified: 08/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45296

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9c7y summary report (pdf.gz) Map-9c7y FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

EM map Of Respiratory Syncytial Virus Polymerase in complex with JNJ-2729

EMD-45296

Single-particle
3.24 Å
EMD-45296
3D View Gallery
Deposition: 11/06/2024
Map released: 08/01/2025
Last modified: 08/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Human respiratory syncytial virus A2
Sample: Respiratory syncytial virus polymerase in complex with non-nucleoside inhibitor
Fitted models: 9c7y

Deposition Authors: Yin Y, Tran MT , Yu X, Jonckers T
Structure-Activity Relationship of Oxacyclo- and Triazolo-Containing Respiratory Syncytial Virus Polymerase Inhibitors.
Tran MT , Grosse S, Carbajo RJ, Jacoby E, Yin Y, Yu X, Martinez C, Stoops B, Cooymans L, Hu L, Lutter FH, Pieters S, Tan E, Alcazar J , Roymans D , van Vlijmen H , Rigaux P, Sharma S, Jonckers THM
(2024) Acs Med.Chem.Lett. , 15 , 1549 - 1558
PUBMED: 39291020
DOI: doi:10.1021/acsmedchemlett.4c00272
ISSN: 1948-5875
Grant Support: