EMD-45242

Single-particle
3.8 Å
EMD-45242
3D View Gallery
Deposition: 07/06/2024
Map released: 31/07/2024
Last modified: 14/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45242
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mGluR3 in the presence of the antagonist LY 341495 and positive allosteric modulator VU6023326 class 2

EMD-45242

Single-particle
3.8 Å
EMD-45242
3D View Gallery
Deposition: 07/06/2024
Map released: 31/07/2024
Last modified: 14/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus
Sample: Metabotropic Glutamate Receptor 3 dimer

Deposition Authors: Strauss A , Levitz J
Structural basis of positive allosteric modulation of metabotropic glutamate receptor activation and internalization.
Strauss A , Gonzalez-Hernandez AJ , Lee J , Abreu N, Selvakumar P, Salas-Estrada L , Kristt M , Arefin A , Huynh K, Marx DC, Gilliland K, Melancon BJ, Filizola M , Meyerson J, Levitz J
(2024) Nat Commun , 15 , 6498 - 6498
PUBMED: 39090128
DOI: doi:10.1038/s41467-024-50548-x
ISSN: 2041-1723