EMD-45193

Single-particle
2.99 Å
EMD-45193
3D View Gallery
Deposition: 05/06/2024
Map released: 02/07/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45193

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

V-Shaped, Channel Formed, T2a Nanobody Bound conformation of wild-type human CFTR (sharpened map from cryoSPARC non-uniform refinement)

EMD-45193

Single-particle
2.99 Å
EMD-45193
3D View Gallery
Deposition: 05/06/2024
Map released: 02/07/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Wild-type human CFTR solubilized in digitonin and cholesterol-hemisuccinate plus T2a nanobody in the presence of 2 mM MgATP

Deposition Authors: Hunt JF , Paige AS , Cohen BM , Goldberg PM , Wang C , Loughlin BJ , Kappes JC , Yang Z , Jiang F , Govaerts C , Overtus M , Rich Z

V-Shaped, Channel Formed, T2a Nanobody Bound conformation of wild-type human CFTR (sharpened map from cryoSPARC non-uniform refinement)
Hunt FJ, Paige AS , Cohen BM , Goldberg PM , Wang C , Loughlin BJ , Kappes JC , Yang Z , Jiang F , Govaerts C , Overtus M , Urbatsch IL, Lukacs G
To Be Published