EMD-45088

Single-particle
3.59 Å
EMD-45088
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Deposition: 25/05/2024
Map released: 11/09/2024
Last modified: 11/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45088
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Cryo-EM structure of an autoinhibited MKLN1 tetramer

EMD-45088

Single-particle
3.59 Å
EMD-45088
3D View Gallery
Deposition: 25/05/2024
Map released: 11/09/2024
Last modified: 11/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure an autoinhibited MKLN1 tetramer

Deposition Authors: Chana CK, Keszei AFA, Sicheri F
FAM72A degrades UNG2 through the GID/CTLH complex to promote mutagenic repair during antibody maturation.
Barbulescu P, Chana CK, Wong MK, Ben Makhlouf I , Bruce JP, Feng Y , Keszei AFA, Wong C, Mohamad-Ramshan R, McGary LC, Kashem MA , Ceccarelli DF , Orlicky S, Fang Y, Kuang H, Mazhab-Jafari M, Pezo RC, Bhagwat AS , Pugh TJ , Gingras AC , Sicheri F , Martin A
(2024) Nat Commun , 15 , 7541 - 7541
PUBMED: 39215025
DOI: doi:10.1038/s41467-024-52009-x
ISSN: 2041-1723