EMD-44962

Single-particle
4.1 Å
EMD-44962
3D View Gallery
Deposition: 21/05/2024
Map released: 25/06/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44962
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9bw9 summary report (pdf.gz) Map and 9bw9 FULL report (pdf.gz)
EMICSS annotations (xml)

Tetrameric Complex of full-length HIV-1 integrase protein bound to the integrase binding domain of LEDGF/p75

EMD-44962

Single-particle
4.1 Å
EMD-44962
3D View Gallery
Deposition: 21/05/2024
Map released: 25/06/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: HIV type 1, Homo sapiens, HIV-1 06TG.HT008
Sample: Full-length tetrameric HIV-1 integrase bound to LEDGF IBD
Fitted models: 9bw9

Deposition Authors: Jing T , Shan Z , Lyumkis D , Biswas A
Oligomeric HIV-1 integrase structures reveal functional plasticity for intasome assembly and RNA binding.
Jing T , Shan Z , Dinh T , Biswas A , Jang S, Greenwood J, Li M , Zhang Z, Gray G, Shin HJ, Zhou B, Passos D, Strutzenberg TS, Aiyer S , Andrade L , Zhang Y , Li Z, Craigie R, Engelman AN , Kvaratskhelia M , Lyumkis D
(2025) Nat Commun , 16 , 9430 - 9430
PUBMED: 41136407
DOI: doi:10.1038/s41467-025-64479-8
ISSN: 2041-1723