EMD-44462
Cryo-EM structure of cardiac amyloid fibril from a variant ATTRV122delta, single filament morphology
EMD-44462
Helical reconstruction3.63 Å
Deposition: 12/04/2024Map released: 15/10/2025
Last modified: 29/04/2026
Sample Organism:
Homo sapiens
Sample: fibril of ATTRV122delta
Fitted models: 9bdm
Deposition Authors: Nguyen BA
,
Ahmed Y
,
Saelices L
Sample: fibril of ATTRV122delta
Fitted models: 9bdm
Deposition Authors: Nguyen BA
,
Ahmed Y
,
Saelices L
Amyloid fibril polymorphism in the heart and liver of a patient with polyneuropathic ATTRv-V122 Delta amyloidosis
Ahmed Y
,
Nguyen BA
,
Kelly C,
Afrin S,
Singh V,
Evers BM,
Shelton JM,
Lopez Escobar C,
Singh P,
Pedretti R,
Wang L,
Bassett P,
Fernandez-Ramirez MDC,
Pekala M,
Lemoff A,
Kluve-Beckerman B,
Saelices L
(2026) Commun Biol
,
Nguyen BA
,
Kelly C,
Afrin S,
Singh V,
Evers BM,
Shelton JM,
Lopez Escobar C,
Singh P,
Pedretti R,
Wang L,
Bassett P,
Fernandez-Ramirez MDC,
Pekala M,
Lemoff A,
Kluve-Beckerman B,
Saelices L
(2026) Commun Biol
Grant Support:
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): DP2-HL163810 (United States)
- American Heart Association: 847236 (United States)
- Welch Foundation: I-2121-20220331 (United States)
