EMD-44154

Helical reconstruction
3.5 Å
EMD-44154
3D View Gallery
Deposition: 20/03/2024
Map released: 29/05/2024
Last modified: 11/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44154

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9b3r summary report (pdf.gz) Map-9b3r FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The structure of human cardiac F-actin

EMD-44154

Helical reconstruction
3.5 Å
EMD-44154
3D View Gallery
Deposition: 20/03/2024
Map released: 29/05/2024
Last modified: 11/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Spodoptera frugiperda, Homo sapiens
Sample: Human cardiac F-actin
Fitted models: 9b3r

Deposition Authors: Doran MH, Sousa D, Rynkiewicz MJ, Lehman W, Cammarato A
The hypertrophic cardiomyopathy-associated A331P actin variant enhances basal contractile activity and elicits resting muscle dysfunction.
Doran MH, Rynkiewicz MJ, Despond E, Viswanathan MC, Madan A, Chitre K, Fenwick AJ, Sousa D, Lehman W, Dawson JF, Cammarato A
(2025) iScience , 28 , 111816 - 111816
PUBMED: 39981516
DOI: doi:10.1016/j.isci.2025.111816
ISSN: 2589-0042