EMDB EMD-4404

Single particle reconstruction
3.93Å resolution

eIF2B:eIF2 complex, phosphorylated on eIF2 alpha serine 52.

Map released:
Last modified:
Overview of EMD-4404
Source organism: Saccharomyces cerevisiae S288C [559292]
Fitted atomic model: 6i3m
Related EM entry by publication: EMD-4428
Primary publication:
The structural basis of translational control by eIF2 phosphorylation.
Adomavicius T, Guaita M, Zhou Y, Jennings MD, Latif Z, Roseman AM, Pavitt GD
Nat Commun 10 2136-2136 (2019)
PMID: 31086188

Function and Biology Details

Sample name: Complex of translation initiation factors eIF2 and eIF2B
Proteins: Complex of translation initiation factors eIF2 and eIF2B, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit delta, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit epsilon, Translation initiation factor eIF-2B subunit gamma, Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma

Experimental Information Details

Resolution: 3.93Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C2
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 QUANTUM (4k x 4k)