EMD-4403

Helical reconstruction
24.0 Å
EMD-4403
3D View Gallery
Deposition: 05/11/2018
Map released: 30/01/2019
Last modified: 06/03/2019
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-4403

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Electron microscopy map of human IMPDH isoform 1 bound to ATP in 150 g/L Ficoll-70

EMD-4403

Helical reconstruction
24.0 Å
EMD-4403
3D View Gallery
Deposition: 05/11/2018
Map released: 30/01/2019
Last modified: 06/03/2019
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: filaments of human IMP dehydrogenase isoform 1 in complex with ATP

Deposition Authors: Martin-Benito J, Nunez R, Fernandez-Justel D, Revuelta JL, Buey RM
A Nucleotide-Dependent Conformational Switch Controls the Polymerization of Human IMP Dehydrogenases to Modulate their Catalytic Activity.
Fernandez-Justel D, Nunez R, Martin-Benito J, Jimeno D , Gonzalez-Lopez A , Soriano EM, Revuelta JL, Buey RM
(2019) J. Mol. Biol. , 431 , 956 - 969
PUBMED: 30664871
DOI: doi:10.1016/j.jmb.2019.01.020
ISSN: 1089-8638
ASTM: JMOBAK