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EMD-43837

Single-particle
3.0 Å
EMD-43837
3D View Gallery
Deposition: 27/02/2024
Map released: 17/04/2024
Last modified: 22/05/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-43837
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

Local refinement map of CaSR extracellular domain in nanodisc-reconstituted human CaSR-miniGisq complex

EMD-43837

Single-particle
3.0 Å
EMD-43837
3D View Gallery
Deposition: 27/02/2024
Map released: 17/04/2024
Last modified: 22/05/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Human CaSR in complex with chimeric Gq (miniGisq) protein

Deposition Authors: Zuo H , Park J, Frangaj A , Ye J , Lu G, Manning JJ , Asher WB , Lu Z , Hu G, Wang L, Mendez J , Eng E , Zhang Z, Lin X, Grasucci R, Hendrickson WA , Clarke OB, Javitch JA , Conigrave AD , Fan QR
Promiscuous G-protein activation by the calcium-sensing receptor.
Zuo H , Park J, Frangaj A , Ye J , Lu G, Manning JJ , Asher WB , Lu Z , Hu GB, Wang L, Mendez J , Eng E , Zhang Z, Lin X, Grassucci R, Hendrickson WA , Clarke OB, Javitch JA , Conigrave AD , Fan QR
(2024) Nature , 629 , 481 - 488
PUBMED: 38632411
DOI: doi:10.1038/s41586-024-07331-1
ISSN: 1476-4687
ASTM: NATUAS