EMD-43606

Single-particle
3.4 Å
EMD-43606 Deposition: 02/02/2024
Map released: 20/08/2025
Last modified: 20/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43606

Cryo-EM Structure of DHX36 bound to the cMyc DNA G-quadruplex, Class 2

EMD-43606

Single-particle
3.4 Å
EMD-43606 Deposition: 02/02/2024
Map released: 20/08/2025
Last modified: 20/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Bos taurus, synthetic construct
Sample: Binary Complex of Bos taurus DHX36 bound to a DNA G-quadruplex
Fitted models: 8vx1

Deposition Authors: Banco MT, Ferre-D'Amare AR

Inter-domain synergy enables both DNA and RNA G-quadruplex unwinding by the DEAH-box helicase DHX36