EMD-43556

Composite map
Single-particle
3.3 Å
EMD-43556
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Deposition: 31/01/2024
Map released: 15/01/2025
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43556
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8vve summary report (pdf.gz) Map and 8vve FULL report (pdf.gz)
EMICSS annotations (xml)

Kappa opioid receptor:Galphai protein in complex with inverse agonist norBNI

EMD-43556

Composite map
Single-particle
3.3 Å
EMD-43556
3D View Gallery
Deposition: 31/01/2024
Map released: 15/01/2025
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Kappa opioid receptor in complex with heterotrimeric G protein (Gai/b/g) and inverse agonist norBNI
Fitted models: 8vve

Deposition Authors: Gati C , Motiwala Z , Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N , Shenvi R , Majumdar S
Molecular mechanisms of inverse agonism via kappa-opioid receptor-G protein complexes.
Tyson AS, Khan S, Motiwala Z , Han GW, Zhang Z, Ranjbar M, Styrpejko D, Ramos-Gonzalez N , Woo S , Villers K, Landaker D , Kenakin T , Shenvi R , Majumdar S , Gati C
(2025) Nat Chem Biol , 21 , 1046 - 1057
PUBMED: 39775170
DOI: doi:10.1038/s41589-024-01812-0
ISSN: 1552-4469