EMD-43543

Single-particle
3.54 Å
EMD-43543
3D View Gallery
Deposition: 30/01/2024
Map released: 25/12/2024
Last modified: 29/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43543
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8vux summary report (pdf.gz) Map and 8vux FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human ABC transporter (hABCC1) bound to cGAMP

EMD-43543

Single-particle
3.54 Å
EMD-43543
3D View Gallery
Deposition: 30/01/2024
Map released: 25/12/2024
Last modified: 29/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Homodimer of hABCC1 bound to cGAMP
Fitted models: 8vux

Deposition Authors: Shinde O , Li P
Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export.
Shinde O , Boyer JA , Cambier S, VanPortfliet JJ, Sui X, Yadav GP, Viverette EG, Borgnia MJ, West AP, Zhang Q, Stetson DB, Li P
(2025) Immunity , 58 , 59 - 73.e5
PUBMED: 39765229
DOI: doi:10.1016/j.immuni.2024.12.002
ISSN: 1074-7613
ASTM: IUNIEH