EMD-43533

Single-particle
3.69 Å
EMD-43533
3D View Gallery
Deposition: 29/01/2024
Map released: 13/03/2024
Last modified: 13/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43533

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human liver-type glutaminase, bound with inhibitor Compound 968

EMD-43533

Single-particle
3.69 Å
EMD-43533
3D View Gallery
Deposition: 29/01/2024
Map released: 13/03/2024
Last modified: 13/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Tetrameric form of Glutaminase liver isoform, bound with Compound 968

Deposition Authors: Feng S , Aplin C , Nguyen T-TT, Milano SK, Cerione RA
Filament formation drives catalysis by glutaminase enzymes important in cancer progression.
Feng S , Aplin C , Nguyen TT , Milano SK, Cerione RA
(2024) Nat Commun , 15 , 1971 - 1971
PUBMED: 38438397
DOI: doi:10.1038/s41467-024-46351-3
ISSN: 2041-1723