EMD-43526

Single-particle
3.39 Å
EMD-43526
3D View Gallery
Deposition: 28/01/2024
Map released: 11/09/2024
Last modified: 20/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43526

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8vu5 summary report (pdf.gz) Map-8vu5 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of MPL bound to TPO

EMD-43526

Single-particle
3.39 Å
EMD-43526
3D View Gallery
Deposition: 28/01/2024
Map released: 11/09/2024
Last modified: 20/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Thrombopoietin bound to thrombopoietin receptor
Fitted models: 8vu5

Deposition Authors: Bratkowski M, Hao Q, Paddock M
Structural basis of MPL activation by thrombopoietin.
Mafi A, Bratkowski M, Geng J, Brito AA, Sridar J , Hu D, Darcy AT, Nanavati D, Brown NJ, Rathinaswamy MK, Kutskova Y, Eaton D, Hao Q, Paddock M
(2024) Blood Vessels, Thrombosis and Hemostasis , 1 , 100018 - 100018
PUBMED: 40766813
DOI: doi:10.1016/j.bvth.2024.100018
ISSN: 2950-3272
Grant Support: