EMD-43507

Single-particle
3.8 Å
EMD-43507
3D View Gallery
Deposition: 24/01/2024
Map released: 11/06/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43507

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8vsv summary report (pdf.gz) Map-8vsv FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of SINV/EEEV in complex with a potently neutralizing intact human antibody EEEV-373

EMD-43507

Single-particle
3.8 Å
EMD-43507
3D View Gallery
Deposition: 24/01/2024
Map released: 11/06/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Eastern equine encephalitis virus, Culiseta melanura
Sample: EEEV in complex with IgG EEEV-373
Fitted models: 8vsv

Deposition Authors: Bandyopadhyay A , Klose T , Kuhn RJ
Structural elucidation of a unique binding mode by an intact alphavirus human IgG molecule to a quaternary epitope.
Bandyopadhyay A , Williamson LE , Sirohi D, Bailey K, Gilliland Jr T, Klose T , Buda G, Trivette A, Sun C, Julander JG, Klimstra WB, Crowe Jr JE , Kuhn RJ
(2025) Nat Commun , 16 , 7716 - 7716
PUBMED: 40830099
DOI: doi:10.1038/s41467-025-60505-x
ISSN: 2041-1723