Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-43499
Engineered peptide-specific binder in complex with HLA-DR1/CLIP
EMD-43499
Single-particle2.28 Å
Deposition: 24/01/2024Map released: 02/10/2024
Last modified: 29/10/2025
Sample Organism:
Homo sapiens,
Metamycoplasma arthritidis
Sample: Engineered peptide-specific binder in complex with HLA-DR1/CLIP
Fitted models: 8vsj
Deposition Authors: Jude KM
,
Yang X,
Du H,
Kassardjian A ,
Julien J-P,
Huang P,
Garcia KC
Sample: Engineered peptide-specific binder in complex with HLA-DR1/CLIP
Fitted models: 8vsj
Deposition Authors: Jude KM
,
Yang X,
Du H,
Kassardjian A ,
Julien J-P,
Huang P,
Garcia KC
A general system for targeting MHC class II-antigen complex via a single adaptable loop.
Du H,
Liu J,
Jude KM ,
Yang X,
Li Y,
Bell B,
Yang H,
Kassardjian A ,
Blackson W ,
Mobedi A,
Parekh U,
Parra Sperberg RA,
Julien JP ,
Mellins ED ,
Garcia KC ,
Huang PS
(2025) Nat Biotechnol , 43 , 1673 - 1682
,
Yang X,
Li Y,
Bell B,
Yang H,
Kassardjian A ,
Blackson W ,
Mobedi A,
Parekh U,
Parra Sperberg RA,
Julien JP ,
Mellins ED ,
Garcia KC ,
Huang PS
(2025) Nat Biotechnol , 43 , 1673 - 1682
Grant Support: