EMD-43319

Single-particle
2.92 Å
EMD-43319
3D View Gallery
Deposition: 09/01/2024
Map released: 26/06/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43319

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8vkj summary report (pdf.gz) Map-8vkj FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human HGSNAT bound with Acetyl-CoA

EMD-43319

Single-particle
2.92 Å
EMD-43319
3D View Gallery
Deposition: 09/01/2024
Map released: 26/06/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Purified human HGSNAT
Fitted models: 8vkj

Deposition Authors: Li F , Zhao B
Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome.
Zhao B, Cao Z, Zheng Y , Nguyen P, Bowen A , Edwards RH , Stroud RM , Zhou Y , Van Lookeren Campagne M , Li F
(2024) Nat Commun , 15 , 5388 - 5388
PUBMED: 38918376
DOI: doi:10.1038/s41467-024-49614-1
ISSN: 2041-1723