EMD-43172

Single-particle
3.04 Å
EMD-43172
3D View Gallery
Deposition: 18/12/2023
Map released: 19/03/2025
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43172
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8vef summary report (pdf.gz) Map and 8vef FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of antibody T5-1E08 UCA (unmutated common ancestor) in complex with stabilized H1N1 Influenza Hemagglutinin Trimer (A/Kiev/1/57)

EMD-43172

Single-particle
3.04 Å
EMD-43172
3D View Gallery
Deposition: 18/12/2023
Map released: 19/03/2025
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Influenza A virus
Sample: Antibody T5-1E08 UCA Fab in complex with influenza hemagglutinin trimer
Fitted models: 8vef

Deposition Authors: Cerutti G, Shapiro L
Distinct binding modes drive the broad neutralization profile of two persistent influenza hemagglutinin stem-specific antibody lineages.
Mantus GE, Cerutti G, Chambers M, Gillespie RA, Shimberg GD, Spangler A, Gorman J, Zhou T, Shen CH, Kanekiyo M, Kwong PD , Shapiro L, Andrews SF
(2025) Structure , 33 , 869
PUBMED: 40112805
DOI: doi:10.1016/j.str.2025.02.010
ISSN: 0969-2126
ASTM: STRUE6
Grant Support: