EMD-42549

Helical reconstruction
3.1 Å
EMD-42549
3D View Gallery
Deposition: 31/10/2023
Map released: 12/06/2024
Last modified: 31/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42549

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8utt summary report (pdf.gz) Map-8utt FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

KIF1A[1-393] P305L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule

EMD-42549

Helical reconstruction
3.1 Å
EMD-42549
3D View Gallery
Deposition: 31/10/2023
Map released: 12/06/2024
Last modified: 31/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Sus scrofa, Homo sapiens
Sample: KIF1A[1-393] P305L mutant - AMP-PNP two-heads-bound state in complex with a 15R microtubule
Fitted models: 8utt

Deposition Authors: Benoit MPMH , Rao L , Asenjo AB , Gennerich A , Sosa H
Cryo-EM unveils kinesin KIF1A's processivity mechanism and the impact of its pathogenic variant P305L.
Benoit MPMH , Rao L , Asenjo AB , Gennerich A , Sosa H
(2024) Nat Commun , 15 , 5530 - 5530
PUBMED: 38956021
DOI: doi:10.1038/s41467-024-48720-4
ISSN: 2041-1723