EMD-42541

Single-particle
3.5 Å
EMD-42541 Deposition: 31/10/2023
Map released: 09/07/2025
Last modified: 27/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42541

E. coli 70S ribosome with unmodified lys-tRNAPro(GGG) bound to slippery P-site CCC-C codon in the 0 frame

EMD-42541

Single-particle
3.5 Å
EMD-42541 Deposition: 31/10/2023
Map released: 09/07/2025
Last modified: 27/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli
Sample: Ribosomal complex with mRNA and tRNAs in the P and A site
Fitted models: 8utj

Deposition Authors: Kimbrough EM, Dunham CM , Nguyen HA
An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting.
Kimbrough EM, Nguyen HA, Li H , Mattingly JM , Bailey NA , Ning W, Gamper H, Hou YM , Gonzalez RL , Dunham CM
(2025) Nat Commun , 16 , 7392 - 7392
PUBMED: 40789848
DOI: doi:10.1038/s41467-025-62342-4
ISSN: 2041-1723