EMD-42521
Structure of Lassa virus glycoprotein (Josiah) on the surface of VSVdG-Lassa-GPC vaccine particle.
EMD-42521
Single-particle14.0 Å
Deposition: 30/10/2023Map released: 09/04/2025
Last modified: 09/04/2025
Sample Organism:
Lassa virus Josiah
Sample: Lassa virus Josiah
Deposition Authors: Enriquez AS
,
Saphire EO
Sample: Lassa virus Josiah
Deposition Authors: Enriquez AS
,
Saphire EO
Preclinical development of a replication-competent vesicular stomatitis virus-based Lassa virus vaccine candidate advanced into human clinical trials.
Cooper CL ,
Morrow G,
Yuan M,
Postler TS ,
Neal ML,
Cross RW,
Woolsey C ,
Agans KN,
Borisevich V,
McNamara RP,
Atyeo C,
Roy V,
Germosen D,
Hou F,
Li SL,
Reiserova L,
Choi Y,
Wilson A,
Wagner D,
Wallace-Selman O,
Carpov A,
Geng F,
Frederick DJ,
DeStefano J,
Ercolini AM,
Enriquez AS ,
Hastie KM,
Ramos da Silva S,
Sayeed E,
Coleman JW,
Kilianski A,
Alter G,
Saphire EO ,
Aitchison JD,
Geisbert TW,
Gupta SB,
Feinberg MB,
Parks CL
(2025) Ebiomedicine , 114 , 105647 - 105647
,
Morrow G,
Yuan M,
Postler TS ,
Neal ML,
Cross RW,
Woolsey C ,
Agans KN,
Borisevich V,
McNamara RP,
Atyeo C,
Roy V,
Germosen D,
Hou F,
Li SL,
Reiserova L,
Choi Y,
Wilson A,
Wagner D,
Wallace-Selman O,
Carpov A,
Geng F,
Frederick DJ,
DeStefano J,
Ercolini AM,
Enriquez AS ,
Hastie KM,
Ramos da Silva S,
Sayeed E,
Coleman JW,
Kilianski A,
Alter G,
Saphire EO ,
Aitchison JD,
Geisbert TW,
Gupta SB,
Feinberg MB,
Parks CL
(2025) Ebiomedicine , 114 , 105647 - 105647
Grant Support:
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): R01 A1132244 (United States)
- Other private: A08154 (United States)