EMD-42440

Single-particle
6.75 Å
EMD-42440
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Deposition: 20/10/2023
Map released: 06/11/2024
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42440
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Cryo-EM structure of human full-length RAD52 in the presence of fork DNA

EMD-42440

Single-particle
6.75 Å
EMD-42440
3D View Gallery
Deposition: 20/10/2023
Map released: 06/11/2024
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM density of full length human RAD52 DNA repair protein on a fork DNA

Deposition Authors: Razzaghi M , Schnicker NJ , Spies M
The RAD52 double-ring remodels replication forks restricting fork reversal.
Honda M , Razzaghi M , Gaur P , Malacaria E, Marozzi G, Di Biagi L, Aiello FA , Paintsil EA , Stanfield AJ, Deppe BJ, Gakhar L , Schnicker NJ , Spies MA , Pichierri P , Spies M
(2025) Nature , 641 , 512 - 519
PUBMED: 40175552
DOI: doi:10.1038/s41586-025-08753-1
ISSN: 1476-4687
ASTM: NATUAS