EMD-42294
Structure of recombinantly assembled murine alpha-synuclein fibrils
EMD-42294
Helical reconstruction3.1 Å
Deposition: 10/10/2023Map released: 09/10/2024
Last modified: 28/05/2025
Sample Organism:
Mus musculus
Sample: alpha-synuclein
Fitted models: 8uie
Deposition Authors: Zhou Y
,
Sokratian A
Sample: alpha-synuclein
Fitted models: 8uie
Deposition Authors: Zhou Y
,
Sokratian A
Mouse alpha-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases.
Sokratian A ,
Zhou Y ,
Tatli M ,
Burbidge KJ,
Xu E ,
Viverette E,
Donzelli S,
Duda AM ,
Yuan Y,
Li H ,
Strader S ,
Patel N ,
Shiell L ,
Malankhanova T,
Chen O ,
Mazzulli JR ,
Perera L ,
Stahlberg H ,
Borgnia M,
Bartesaghi A ,
Lashuel HA ,
West AB
(2024) Sci Adv , 10 , eadq3539 - eadq3539
,
Zhou Y ,
Tatli M ,
Burbidge KJ,
Xu E ,
Viverette E,
Donzelli S,
Duda AM ,
Yuan Y,
Li H ,
Strader S ,
Patel N ,
Shiell L ,
Malankhanova T,
Chen O ,
Mazzulli JR ,
Perera L ,
Stahlberg H ,
Borgnia M,
Bartesaghi A ,
Lashuel HA ,
West AB
(2024) Sci Adv , 10 , eadq3539 - eadq3539
Grant Support:
- Michael J. Fox Foundation: ASAP-020527 (United States)