EMD-42294

Helical reconstruction
3.1 Å
EMD-42294
3D View Gallery
Deposition: 10/10/2023
Map released: 09/10/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42294
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8uie summary report (pdf.gz) Map and 8uie FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of recombinantly assembled murine alpha-synuclein fibrils

EMD-42294

Helical reconstruction
3.1 Å
EMD-42294
3D View Gallery
Deposition: 10/10/2023
Map released: 09/10/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: alpha-synuclein
Fitted models: 8uie

Deposition Authors: Zhou Y , Sokratian A
Mouse alpha-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases.
Sokratian A , Zhou Y , Tatli M , Burbidge KJ, Xu E , Viverette E, Donzelli S, Duda AM , Yuan Y, Li H , Strader S , Patel N , Shiell L , Malankhanova T, Chen O , Mazzulli JR , Perera L , Stahlberg H , Borgnia M, Bartesaghi A , Lashuel HA , West AB
(2024) Sci Adv , 10 , eadq3539 - eadq3539
PUBMED: 39485845
DOI: doi:10.1126/sciadv.adq3539
ISSN: 2375-2548
Grant Support: