EMD-42178
(Local ABC2) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
EMD-42178
Single-particle3.05 Å
Deposition: 02/10/2023Map released: 16/10/2024
Last modified: 16/10/2024
Sample Organism:
Homo sapiens
Sample: cystic fibrosis transmembrane conductance regulator(CFTR)
Deposition Authors: Hunt JF
,
Wang C ,
Singh S ,
Loughlin BJ,
Yang Z,
Xu H,
Veit G,
Vorobiev S,
Clarke OB,
Jiang F,
Li Y,
Rich Z ,
Menten ER,
Grassucci RA,
Wang W,
Mezzell A,
Fu Z,
Wong K,
Wetmore DR,
Sutton RB,
Brouillette CG,
Urbatsch IL,
Kappes JC,
Lukacs GL,
Frank J,
Cohen BM
Sample: cystic fibrosis transmembrane conductance regulator(CFTR)
Deposition Authors: Hunt JF
,
Wang C ,
Singh S ,
Loughlin BJ,
Yang Z,
Xu H,
Veit G,
Vorobiev S,
Clarke OB,
Jiang F,
Li Y,
Rich Z ,
Menten ER,
Grassucci RA,
Wang W,
Mezzell A,
Fu Z,
Wong K,
Wetmore DR,
Sutton RB,
Brouillette CG,
Urbatsch IL,
Kappes JC,
Lukacs GL,
Frank J,
Cohen BM
Mechanism of dual pharmacological correction and potentiation of human CFTR
Wang C ,
Yang Z,
Loughlin BJ,
Xu H,
Veit G,
Vorobiev S,
Clarke OB,
Jiang F,
Li Y,
Singh S ,
Rich Z ,
Menten ER,
Grassucci RA,
Wang W,
Mezzell A,
Fu Z,
Wong K,
Wetmore DR,
Sutton RB,
Brouillette CG,
Urbatsch IL,
Kappes JC,
Lukacs GL,
Frank J,
Hunt JF ,
Cohen BM
To Be Published
,
Yang Z,
Loughlin BJ,
Xu H,
Veit G,
Vorobiev S,
Clarke OB,
Jiang F,
Li Y,
Singh S ,
Rich Z ,
Menten ER,
Grassucci RA,
Wang W,
Mezzell A,
Fu Z,
Wong K,
Wetmore DR,
Sutton RB,
Brouillette CG,
Urbatsch IL,
Kappes JC,
Lukacs GL,
Frank J,
Hunt JF ,
Cohen BM
To Be Published
Grant Support:
- Cystic Fibrosis Foundation: Hunt18G0 (United States)
- Cystic Fibrosis Foundation: Hunt20G0 (United States)
- Cystic Fibrosis Foundation: HUNT13XX0 (United States)
- Cystic Fibrosis Foundation: 004400G222 (United States)
- Cystic Fibrosis Foundation: FRANK16XX0 (United States)
- Cystic Fibrosis Foundation: FRANK18G0 (United States)